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Stihl fs91 r1/27/2024 ![]() It also increases comfortability and allows for maximum maneuvering. The shoulder strap allows for easy weight distribution while using the trimmer. The spark plug, choke lever, and control cables are all protected to prevent damage. The adjustable front handle has a 360-degree rotation that is easily adjustable and comfortable. This model is very fuel-efficient with its 24oz tank. The user can fit many different trimmer heads and blades on this tool. Gearbox attachments are interchangeable and include a shaft trimmer attachment, straight hedge trimmer attachment, power sweep attachment, bristle brush attachment, blower attachment, and many more. It’s aimed at providing low exhaust emissions to help save the environment. The “Care for Nature” seal identifies Stihl’s reduced-engine emission technology. Here are some of the main features that each model has. This allows them to perform at optimal levels for long periods without issues. Stihl weed trimmers are built with enhanced power to weight ratio. This starter does not take up a lot of room or weigh a lot, like other brands. The full crank system and spring-assisted pull are on the rear. The air filter is also easily accessible, allowing for an easy air filter change. The plastic hides the engine, preventing accidental burns. The construction of the plastic makes for a very safe trimming experience. Stihl is known for constructing very durable trimmers that last long. The max output speed for the Stihl 94R is 7290 RPM. The Stihl 91R max output speed with the cutting attachment is 7150 RPM. To engage the throttle set button, press the operator presence lever by holding the throttle set button while releasing the throttle trigger. The flywheel allows for adjustable speed settings. The trimmer will have the most cutting force at maximum engine speed. ![]() It also has a throttle set button which can be set to maintain a certain speed without holding down the trigger. Stihl trimmers have a throttle that is pushed down to increase the speed of the trimmer. Stihl engines are known for providing a lot of power while still remaining light and not creating a hassle to carry around. Thanks for your support! You can find out more here. Some links on this page may be affiliate links which means if you choose to make a purchase, I may earn a small commission at no extra cost to you. By the way, our site is supported by visitors like you.
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Wall mount cable hider1/27/2024 ![]() Lastly, this box does not require tools or assembly of any type, which means all you have to do is remove it from its packaging and place where you’d like to transform cable clutter. It weighs a mere 2.09 pounds, making it a breeze to move around the house on a whim. ![]() In addition to an appealing but roomy minimalist build, this box boasts an ultra-lightweight feel. We also wish this box came with its own power strip, but you’ll need to provide one. Though the Yamazaki accommodates strips and cords that may have trouble fitting in other cable-concealing boxes, not all options will fit. This 15.7-inch wide box is suitable for longer extension cords and power strips with up to seven outlets. This design comes in three neutral colors, including white, black, and gray, so you’re bound to find a hue to blend right into your surroundings. This material allows for its sleek stature, as well as its durability and overall safety. While the plastic exterior may give you doubts about this box’s durability, it’s a sturdy, heat-resistant PC-ABS resin. With its unobtrusive rectangular white design and capacity to accommodate bulky power strips and tiny tangles of wire alike, the Yamazaki Home Cable Management Box is a cord-concealing hit for virtually any scenario, from both a form and function standpoint. The Spruce Home Improvement Review Board.
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Naked models pussy1/27/2024 Miley Cyrus (Age 26) is an American singer, songwriter, and actress. I would like to see her leaked threesome sex tape, with a girl and a man in the same bed! We’re gonna start with Miley Cyrus naked leaked photos and after that her sex tape porn, then we will go with the flow! Despite all problems she had in previous relationships, now we know Cyrus is bisexual. ![]() Wild and crazy Miley had so many problems with her iCloud, but we all love her naughty side. This is not nakedness under a veil of nudity, this is nakedness as power.Check out the ultimate collection of Miley Cyrus nude leaked pics where she showed her hot pussy, and also a porn video of the personal sex tape! It portrays the body through beautiful, disruptive, and experimental lenses, subverting the historically dominant male gaze and celebrating the human form in all its rich variety. I think everyone will find at least one photographer they like in this show!’Īlthough broad and complex in content, the curatorial focus of ‘Nude’ is distilled. ‘What I’m showing isn't necessarily underrepresented bodies, and I do personally feel there is an issue to see this as a virtue in itself what happens when these bodies have been represented for a while? Are they all of a sudden irrelevant? With that said, it is very exciting and fun to see works in a wide array of expressions including different body shapes. It’s a photo that I love but that is very hard to post and show through the big online platforms, so I am very happy to show it to a wide audience,’ she says. ‘I also have a photo of my friend Adam Pettersson’s bum and balls through Lazoschmidl underwear with a cherry on top. Her work also alludes to the tension between nudity and censorship on social media, which is the subject of fierce debate. It is very important to me to do everything to deconstruct this hegemony, I am committed to invoking all these fights until they are won.’Īrvida Byström is presenting Cherry Picking. The series is a mix of still lifes and selfies, both of which have been feminised and dismissed as ‘low brow', according to the artist. ‘I am focused on giving a voice and visibility to those who are not or too little represented. It necessarily involves the other senses because it is impossible not to see, hear and smell people when you are close enough to touch them.’īut why does Pittaluga think it's important for contemporary photography to offer visibility to all body types? ‘I hope that one day this kind of question will no longer exist,’ she says. What interests me nudity, from a pictorial and emotional point of view, is the expression of the skin. The more body types we are exposed to, the more pragmatic our view will become.’įrench-Uruguayan photographer Bettina Pittaluga’s work in ‘Nude’ focuses on physical intimacy, which, as the artist explains, ‘can be revealed by being in someone’s personal space, or bonding through physical contact, by skinship. I created a series where I framed my models as sculptures and works of art in the hope that the viewer will suspend any judgments about whether they find the models sexually attractive or not, or whether their bodies are socially “acceptable”. ![]() Seeing nudes in a museum is one of the only exceptions to this. ![]() ‘In the US, what little nudity permitted is usually shown in a sexual context. ‘Most of the bodies we see online on a daily basis aren’t even real, but rather enhanced or modified by technology to conform to a current, unsustainable trend,’ says LA-based photographer Julia SH, who is exhibiting powerful, textured portraits of bodies rarely depicted in 21st-century media, presented in museum-like frames. But under this flawless skin is a rotten deception, one deepened by a social-media saturated society.
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1988 ohio state football roster1/27/2024 He threw a 72-yard touchdown pass to Jayden Ballard against Toledo in 2022.That 85-yard pass play was the third-longest pass in school history and the sixth-longest play from scrimmage.His long pass was an 85-yard catch-and-run connection with Emeka Egbuka, also coming against the Zips.Completed 13 of 18 passing attempts for 319 yards and two touchdowns in his start vs.Played in seven games in 2022 after earning his first varsity letter in 2021 as a true freshman, playing in five games.In his second season with the program and has three seasons of eligibility and has thrown for 606 yards with three touchdowns and two interceptions Has a career completion percentage of 70.6 pct.Has played in 12 games the past two seasons with a start in 2021 vs.He is a true junior with two seasons of eligibility remaining.Kyle enters his third season with the Buckeyes in 2023 as the most experienced quarterback on the roster.Boston also broke his own single-season reception mark and moved past Cris Carter on the school's all-time yardage list. Joe Germaine completed 19-of-24 passes for 330 yards, his seventh career 300-yard game, and his favorite target was David Boston, who finished with 10 receptions for 217 yards, most ever by a Michigan opponent. Ohio State secured a share of its 28th Big Ten title as the fans stormed the field with less than 30 seconds to play. OSU – David Boston – 10 receptions, 217 yards, 2 TD.MICH – Tai Streets – 9 receptions, 118 yards, TD.OSU – Michael Wiley – 12 rushes, 120 yards, TD.MICH – Clarence Williams – 11 rushes, 13 yards.OSU – Joe Germaine – 16/28, 330 yards, 3 TD.MICH – Tom Brady – 31/56, 375 yards, TD, 2 INT.MICH – Jay Feely 30-yard field goal, 14:47.OSU – Dan Stultz 39-yard field goal, 1:36.MICH – Jay Feely 34-yard field goal, 4:47.OSU - David Boston 43-yard pass from Joe Germaine (Dan Stultz kick), 9:51.MICH – Tai Streets 3-yard pass from Tom Brady (Jay Feely kick), 0:25.OSU – David Boston 30-yard pass from Joe Germaine (Dan Stultz kick), 4:03.MICH – Jay Feely 27-yard field goal, 14:33. ![]()
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Macos 10.14 compatibility1/27/2024 From macOS 10.15 and higher, the operability of some NI legacy hardware is terminated.Read more about updating the firmware of your device in this article. We strongly recommend to download and install the latest Device Updater from our Drivers & Other Files page in order to avoid possible functionality issues. Most of the devices listed below offer a Device Updater to update the firmware installed on your device.The earlier MK1 versions are therefore not officially supported on macOS 11 (or higher). ![]() Devices labeled MK2 (or MK3) are later-generation models that run on class-compliant driver technology.If a device is not listed below, this means it is not supported by these macOS systems.These devices do not require a driver installation and work simply by connecting them to the computer. Only current generation class-compliant devices are supported in these macOS systems.We will continue to conduct systematic tests with macOS 13 Ventura to offer full compatibility with our software and hardware products as soon as possible. Please find the latest info about compatibility with Apple Silicon in this article. This includes MASCHINE MK1, MASCHINE MIKRO MK1, AUDIO 2 / 4 / 8 DJ, TRAKTOR AUDIO 2 MK1, and TRAKTOR KONTROL S2 / S4 / X1 MK1. The same applies to macOS 11 (Big Sur), macOS 12 (Monterey), and macOS 13 (Ventura). macOS 10.15 (Catalina) terminated the operability of some legacy NI hardware.All products listed here require the latest update from Native Access, as well as the latest version of macOS 13 (Ventura).Other Native Instruments software and hardware products are not officially supported on macOS 13 Ventura. These hardware devices are compatible with macOS 13 Ventura: Hardware Product Important note: If the installation fails in Native Access, please follow the steps in this article. Here you can learn how to do this.Ĭurrently, the latest versions of the following software products are supported on macOS 13 Ventura: Software Product ![]() Note: To use the plug-in versions of the products that are compatible via Rosetta 2 only, it is necessary to start your DAW using Rosetta. This can be worked around by closing and reopening the plug-in window. **There may be Cutoff UI or UI glitches when the REAKTOR 6 AU plug-in window resizes on content load. *Native Pro Tools / AAX plug-in support on Apple Silicon. The Komplete Effects are: Crush Pack (Bite, Dirt, Freak), Driver, Mod Pack (Choral, Flair, Phasis), Premium Tube Series (Enhanced EQ, Passive EQ, Vari Comp), Solid Mix Series (Solid Bus Comp, Solid EQ, Solid Dynamics), Raum, Replika, Replika XT, Reverb Classics (RC24, RC48), Supercharger, Supercharger GT, Transient Master, Vintage Compressors (VC 160, VC 2A, VC 76).
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![]() Through developmental mechanisms and further differentiation in the periphery, several phenotypically distinct circulating B cell subpopulations are generated ( Allman and Pillai, 2008). Both direct switching and sequential switching upon a second round of antigen exposure have been reported ( Horns et al., 2016 Cameron et al., 2003 Zhang et al., 1994). Class switching is an essential mechanism during humoral immune responses as the constant region of an antibody determines its effector function ( Vidarsson et al., 2014). This process involves the replacement of the proximal heavy chain constant gene by a more distal gene. Subsequently, B cells with a mutated BCR providing increased antigen affinity are selected and show increased survival and proliferation capacity ( Zheng et al., 2005).įurthermore, class switch recombination (CSR) modifies the IgH constant region, resulting in the generation of B cells with nine different immunoglobulin isotypes or isotype subclasses, namely IgD, IgM, IgG1-4, IgA1/2 and IgE ( Stavnezer et al., 2008). Further development of B cells occurs in the periphery in response to stimulation with the process of somatic hypermutation (SHM) through which point mutations are introduced in the genes coding for the V(D)J part of the immunoglobulin heavy (IgH) and light chain ( Jolly et al., 1996). The generation of the heavy and light chain of the BCR is mediated by the random and imprecise process of V(D)J recombination ( Tonegawa, 1983). Introductionī cell development starts in the bone marrow where immature B cells must assemble and express on their surface a functional but non-self-reactive B cell antigen receptor (BCR) ( Lefranc and Lefranc, 2001). Overall, this study provides unprecedented insight over mechanisms of B cell repertoire control in peripherally circulating B cell subpopulations. Furthermore, certain IgH repertoire characteristics correlated with the position of the constant region on the IgH locus. Sorted subpopulations shared similar repertoire characteristics with their corresponding in silico separated subsets. Using advanced bioinformatic analysis and machine learning, we show that sorted B cell subpopulations are characterised by distinct repertoire characteristics on both the individual sequence and the repertoire level. Here, we sequenced the IgH repertoire of naïve, marginal zone, switched and plasma cells from 10 healthy adults along with matched unsorted and in silico separated CD19 + bulk B cells. These cells undergo developmental and maturational changes involving VDJ recombination, somatic hypermutation and class switch recombination, altogether shaping their immunoglobulin heavy chain (IgH) repertoire. Several human B cell subpopulations are recognised in the peripheral blood, which play distinct roles in the humoral immune response.
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Diablo 4 screenshots1/27/2024 ![]() Side Quests Keeping the Old Traditions Quest Walkthrough Secret of the Springs Quest Guide Unyielding Flesh Quest Brought to Heel Walkthrough The Pilgrim's Footsteps Quest Walkthrough The Malady Of The Soul Quest Chain Guide Reject the Mother Quest Guide Guide To The Sorcerer: Legacy of the Magi Quest One Diablo 4 Side Quest Takes Lilith's Sin to the Next Level The Swamp's Protection Walkthrough Blood and Sweat Quest Walkthrough (Where to Find Little Tuya) Salt Begets Salt Quest Guide By Three They Come Cinematic Location (To Walk a Dark Path Walkthrough) 7 Most Terrifying Quests And Where To Find Them The Traveler’s Prayer Quest Walkthrough The Traveler's Superstition Quest Walkthrough The Heretic Quest Chain Guide Consumed by Pride Quest Guide Closing the Book (Collect the Ledger Pages) Quest Guide Greater Good Quest Guide Guide To The Sanguine Chapel (Includes the Blood Sermon Quest) Guide To The Sanguine Chapel (Includes the Blood Sermon Quest) A Sodden Pact Quest Guide A Sodden Pact Quest Guide Way of the Three Guide (Hidden Prime Evils Quest) Way of the Three Guide (Hidden Prime Evils Quest) All 214 Side Quests All 214 Side Quests
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White farmhouse kitchen decor1/26/2024 Patinated pieces are great for adding a lot of texture and visual interest without straying from the rustic sensibilities of the farmhouse style. 'Consider also looking beyond furniture to salvaged materials you can restore into something new, such as lighting fixtures, kitchen hardware and basic décor items. ![]() Look to antique bar stools and tables in classic shapes for a more lived-in feel,' she says. 'Introducing well-loved furniture is an easy way to make your kitchen feel more rustic. You could buy new, but Anne Haimes, founder of Anne Haimes Interiors, suggests including reclaimed pieces, too. 'Windsor back chairs or linen-upholstered chairs and a rustic harvest table are my farmhouse kitchen furniture tips,' says designer Sarah Mandell from Aspen & Ivy. Find a place to hide them in the bottom cabinets,' advises Stephany. 'Smaller appliances such as mixers, coffee makers, toaster ovens, etc, can clutter up countertops, making the space less inviting. Organizing kitchen countertops is key if you want to stop your relaxed farmhouse look tipping into messy and cluttered. Buying a range oven will be another authentic addition to a farmhouse kitchen. 'Since farmhouse kitchens are designed to accommodate large gatherings, a double-wall oven can serve all your guests,' says Stephany. Similarly, a gas cooktop will look more traditional than an electric one. Stephany suggests disguising a built-in refrigerator with custom panelling that matches the rest of the cabinetry and gives an authentic feel. Additionally, stainless steel is easy to clean and has long-term value,' says Stephany Smith, home improvement expert at Fantastic Services. Stainless-steel kitchen appliances work beautifully within any kitchen. Typically, farmhouse kitchens feature appliances that blend in well with the color palette. ![]() 'To keep the comfortable and cozy aesthetic, your appliances need to be fully functional and high-tech without throwing off the farmhouse character. Decorate in country colorsĪsking how do I make my kitchen look farmhouse? Think: a combination of functionality and style, so any kitchen appliances should fit the look you want to create. ![]() While white is still a great option for farmhouse kitchens, darker colors can work just as well and add more depth to a space.' 8. 'You also can get more creative with the color of your shiplap. This will create the optical illusion of taller ceilings and draw the eye upwards – perfect if you want to highlight any open shelving. 'Instead of positioning the shiplap in a horizontal formation, try placing the cladding vertically. 'Although design experts have been ruminating on whether shiplap cladding is officially out of style – and certainly it’s true for coastal-themed rooms – I’d argue they make the perfect textural addition to farmhouse kitchens,' says interior designer Anne Haimes. Farmhouse kitchen wall decor might include tile, shelving and display areas, kitchen wallpaper ideas, and wall paneling. While cabinets may cover much of the wall in your kitchen, there should still be plenty of space to consider how to use farmhouse decor ideas can enhance this vertical space.
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![]() To keep stress levels low when sharing finances, it helps to know your partner’s financial situation, because with joint accounts and mortgages, for better or worse, you’re in it together. A smaller proportion (14%) said they feel more stressed about money after sharing, while the remainder (41%) said that not much has changed – their stress levels related to money are as high or low as ever. Sharing money can turn an impossible dream into reality, but does sharing finances with one’s other half reliably reduce stress?Ĥ5% said they feel less stress after sharing finances with their partner compared to when they kept their money separate. While many couple take out life insurance when buying a property, it's available to renters too. Just as there are decisions to be made about splitting house costs equally, life insurance is another financial arrangement that can be taken out on a single or joint basis. While many couples take out life insurance when, it’s available to too. Just as there are decisions to be made about splitting housing costs equally, life insurance is another financial arrangement that can be taken out on a basis. 52% who rent said it would be more difficult to do so without their partners’ financial contributions, and 20% said renting would be impossible. It’s a similar story for cohabiting couples who rent their homes. ![]() Half of cohabiting couples with mortgages in their 20s (49%) said it would have been ‘slightly more difficult’ or ‘much more difficult’ to buy without pooling their money, but 28% said it would have been completely impossible.Įven among couples over the age of 40, many of whom got onto the property ladder when house prices were lower, 1 in 5 said securing a mortgage without their partner would have been impossible. For many people, the only way to become a first-time buyer is to step onto the ladder with their partner. The average UK house price in September 2019 was £234,000, £3,000 higher than the previous year. 7 in 10 couples said getting a mortgage would have been more difficult or impossible without pooling their finances However, the most common reason was simply that they’ve never considered pooling their wealth (36%), which is surprising because sharing finances helps couples overcome their biggest financial hurdles. 51% said they’d consider sharing all the money they own in a joint account with their partner, but the other 49% would not.Ībout 1 in 6 couples without a joint account wouldn’t consider getting one because it’d make breaking up complicated, while 1 in 7 don’t want their partner spending money they’ve earned. Couples that haven’t opened a joint account are on the fence about taking this step. The main feature of a joint account is that both partners have equal access and ownership of the money it holds, regardless of who earned the money. Joint accounts are more common among married couples – 91% of joint account holders have tied the knot, compared to 55% of those with only separate accounts. Or, the same set-up but with equal contributions regardless of their earnings (14%). For example, separate accounts for most things but a joint account for expenses, to which partner’s contribute based on their earnings (16%). Most couples fall into one of two camps, either sharing all of their income and savings in joint accounts (32%) or keeping their finances completely separate in individual accounts (32%). The majority of cohabiting couples share all their money or keep it entirely separate To explore how finances are shared and separated in Britain today, we surveyed 1,052 people who live with their partners. In fact, while married couples who live together are still the norm, unmarried cohabiting couples – whose money is separate in the eyes of the law – are now the fastest-growing family type.Īt the same time, with a bank account and app for every financial task, couples now have more choice than ever in how they manage their money, either as a team or two individuals. Couples are increasingly choosing to live together before, or without, getting married.
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Drug dossier meaning1/26/2024 A DMF is a submission to the FDA that may be used to provide confidential detailed information about facilities, processes, or articles used in the manufacturing, processing, packaging, and storing of one or more human drugs.įDA means the United States Food and Drug Administration. ![]() Marketing Authorization Application or “MAA” means an application to the appropriate Regulatory Authority for approval to sell the Product (but excluding Pricing Approval) in any particular country or regulatory jurisdiction.ĭrug Approval Application means a New Drug Application as defined in the FFDCA or any corresponding foreign application in the Territory, including, with respect to the European Union, a Marketing Authorization Application filed with the EMA pursuant to the centralized approval procedure or with the applicable Regulatory Authority of a country in Europe with respect to the mutual recognition or any other national approval.ĪNDA means abbreviated new drug application.ĭrug Application means a new drug application, an abbreviated drug application, or a product license application for any Product, as appropriate, as those terms are defined in the FDCA.ĭrug Master File or “DMF” is described in 21 C.F.R. MFDA means the Mutual Fund Dealers Association of Canada īLA means basic liquidity adjustment which is 0% or 25% as determined by Fitch in accordance with the Fitch Criteria Once a study is completed and placed into the Drug Dossier, either party and/or both parties may use that study without further compensation.ĭrug abuse means any pattern of pathological use of drugs that causes impairment in social or occupational functioning, or that produces physiological dependency evidenced by physical tolerance or by physical symptoms when it is withdrawn. The board identifies the key stakeholders with an interest in the charity’s work. ![]() Natural and technological disasters will greatly increase the scope of search and rescue operations. ![]() P&G shall use commercially reasonable efforts to aid API in the preparation of documents to be filed as part of any application for the Health Registration with any applicable Ministry of Health within the Secondary Co-Promotion Territory and the analysis of data derived from studies included in the Drug Dossier provided by P&G to API in order to facilitate timely filings by API with any applicable Ministry of Health. To facilitate the sub-licensee’s efforts to obtain such Health Registrations, API shall have the right to provide to such sub-licensee a copy of the Drug Dossier, or the appropriate components thereof. Thereafter, the Investigation New Drug Dossier (IND) was submitted and approved by the FDA in September 2018. To facilitate API’s efforts to obtain such Health Registrations with respect to its Product, P&G shall provide to API access to all non-clinical and clinical scientific data with respect to the Product as soon as practicable after the Original Agreement Effective Date and shall provide access to API to the Drug Dossier as soon as practicable. Ancillary Dossier (Appendix 2: Ancillary Drug Dossier Requirement for Medical Device-Drug Combination Product) NPRA shall issue an endorsement letter upon satisfactory evaluation.ĪNCILLARY COMPONENT DETAILS Please provide details of the ancillary component according to the following: - Ancillary Medical Device Dossier (refer Appendix 2 of Guideline For Registration of Drug- Medical Device and Medical Device-Drug Combination Products)- Ancillary Drug Dossier (refer Appendix 3 of Guideline For Registration of Drug-Medical Device and Medical Device-Drug Combination Products) 5.ĪPI shall have access to all marketing, promotional and sales materials and clinical data previously developed in the Territory with respect to the Product, including the Drug Dossier. |